SCHEMBL6780549

SCHEMBL6780549

O=C(O)C1=CN2C=CNc3cccc(c32)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6667852 0.88
Bromide SCHEMBL6666428 0.86
SCHEMBL10758980 0.80 GAA (0.30) GAAMAPT
SCHEMBL607506 0.75 NOTUM (0.32)
SCHEMBL9032487 0.67 MAOA (0.31)
SCHEMBL11202182 0.66 NOTUM (0.39) MAPT
Hydrochloric Acid SCHEMBL9223535 0.66 PARP1 (0.31)
SCHEMBL28414326 0.66 NOTUM (0.31) GAA
Hydrochloric Acid SCHEMBL10432400 0.65 NOTUM (0.38) MAPT
SCHEMBL9227676 0.65 GAA (0.33) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686356-B2 HERPES VIRUS PHARMACIA & UPJOHN COMPANY 2004-02-03 US disclosed
US-5237060-A Cyclization; amination BAYER AKTIENGESELLSCHAFT (DE) 1993-08-17 US disclosed
US-4499270-A INHIBITING THE GROWTH OF MICROORGANISMS RIKER LABORATORIES, INC. (US) 1985-02-12 US disclosed
US-4348521-A BACTERICIDES, FUNGICIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-09-07 US disclosed