Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10432400 | 0.98 | NOTUM (0.38) | NOTUMMEN1MAPTKMT2AKDM4E | |
| SCHEMBL8775599 | 0.91 | MCL1 (0.40) | NOTUMMEN1KMT2AHTR2CMCL1 | |
| SCHEMBL9273390 | 0.81 | MCL1 (0.39) | NOTUMKMT2AKDM4EPOLBTSHR | |
| SCHEMBL28414326 | 0.74 | NOTUM (0.31) | NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL9227676 | 0.73 | GAA (0.33) | NOTUMMEN1MAPTKMT2AKDM4E | |
| SCHEMBL11724902 | 0.72 | SRD5A2 (0.34) | — | |
| SCHEMBL6780552 | 0.72 | TRPA1 (0.35) | — | |
| Water SCHEMBL10588716 | 0.72 | MAOA (0.34) | — | |
| Hydrochloric Acid SCHEMBL10435581 | 0.72 | GAA (0.33) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL7210084 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4416884-A | ANTIBIOTIC, BACTERICIDE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-22 | — | — | US | disclosed |