Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507485 | 0.88 | SNCA (0.37) | SNCATLR9TLR7APPMAOB | |
| SCHEMBL9509488 | 0.84 | MAPT (0.39) | APPTSHRCRHR1MAPTALDH1A1 | |
| SCHEMBL9509841 | 0.81 | TLR9 (0.42) | SNCATLR9TLR7APPMAOB | |
| SCHEMBL10887641 | 0.78 | APP (0.46) | SNCATLR9TLR7APPMAOB | |
| SCHEMBL8067213 | 0.77 | MAOB (0.40) | SNCATLR9TLR7APPMAOB | |
| SCHEMBL10888098 | 0.76 | CYP1A2 (0.38) | MEN1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9509806 | 0.75 | SNCA (0.36) | SNCATLR9TLR7APPMAOB | |
| SCHEMBL9508228 | 0.75 | SNCA (0.36) | SNCATLR9TLR7APPMAOB | |
| SCHEMBL6616034 | 0.75 | GAA (0.41) | SNCAAPPMEN1KMT2ACYP1A2 | |
| SCHEMBL8529081 | 0.75 | ACHE (0.40) | SNCAAPPMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831081-B2 | Herpes virus including simplex types 1 and 2, varicella zoster, human cytomegalovirus, Epstein-Barr and human 6, 7 and 8 | PHARMACIA & UPJOHN | 2004-12-14 | — | — | US | disclosed |