⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120183 | 0.87 | — | — | |
| SCHEMBL6782563 | 0.85 | — | — | |
| SCHEMBL1841985 | 0.78 | KDM4E (0.44) | — | |
| SCHEMBL29129120 | 0.75 | ADORA3 (0.41) | — | |
| SCHEMBL7120676 | 0.74 | — | — | |
| SCHEMBL14003304 | 0.73 | BACE1 (0.37) | — | |
| SCHEMBL5334047 | 0.72 | RPS6KA2 (0.35) | — | |
| SCHEMBL12307514 | 0.72 | RPS6KA2 (0.35) | — | |
| SCHEMBL1986577 | 0.72 | GSK3B (0.43) | — | |
| SCHEMBL13623804 | 0.71 | HCAR3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753316-B1 | 3-ACRYLAMIDOPYRAZOLE-5-CARBOXAMIDE DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 2004-06-22 | — | — | US | disclosed |
| EP-0722446-B1 | DISTAMYCIN A ANALOGUES AS ANTITUMOUR OR ANTIVIRAL AGENTS | PHARMACIA ITALIA SPA (IT) | 2002-12-11 | — | — | EP | disclosed |
| US-5753629-A | AMINO ACID DERIVATIVE ANTIBIOTICS; VIRICIDES | PHARMACIA S.P.A. (IT) | 1998-05-19 | — | — | US | disclosed |
| CN-1131946-A | Distamycin A analogues as antitumour or antiviral agents | PHARMACIA SPA (IT) | 1996-09-25 | — | — | CN | disclosed |