Oxalic Acid

Oxalic Acid

SCHEMBL6782335

COc1cccc2sc([C@H]3C[C@H]4CC[C@@H](C3)N4C[C@H](O)COc3cccc4occc34)cc12.O=C(O)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A4 known ✓ P31645 7/20 0.51
HTR1A P08908 18/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL6782339 1.00 HTR1A (0.67) HTR1ASLC6A4
Oxalic Acid SCHEMBL6780205 0.83 HTR1A (0.46) HTR1ASLC6A4
Oxalic Acid SCHEMBL6312730 0.77 HTR1A (0.68) HTR1ASLC6A4
Oxalic Acid SCHEMBL6317600 0.75 HTR1A (0.70) HTR1ASLC6A4
Oxalic Acid SCHEMBL6311056 0.75 HTR1A (0.70) HTR1ASLC6A4
Oxalic Acid SCHEMBL6317196 0.75 HTR1A (0.70) HTR1ASLC6A4
Oxalic Acid SCHEMBL6311323 0.75 HTR1A (0.70) HTR1ASLC6A4
Oxalic Acid SCHEMBL6319489 0.74 HTR1A (0.66) HTR1ASLC6A4
Oxalic Acid SCHEMBL5759602 0.72 HTR1A (0.92) HTR1ASLC6A4
Oxalic Acid SCHEMBL5762245 0.71 HTR1A (0.93) HTR1ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6835733-B2 Useful for treating depression, anxiety, and alleviating the symptoms caused by withdrawal or partial withdrawal from tobacco or nicotine. ELI LILLY AND COMPANY 2004-12-28 US disclosed