SCHEMBL6782736

SCHEMBL6782736

C=CC(=O)OC(CC)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.41
HPGD P15428 1/20 0.39
THRB P10828 4/20 0.37
ALDH1A1 P00352 5/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.34
THRA P10827 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL1568532 0.94 TSHR (0.37) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL17300322 0.86 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL23494166 0.84 THRB (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL28060224 0.84 TSHR (0.38) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL23494171 0.84 TSHR (0.41) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL9709336 0.83 HCAR2 (0.40) TSHR
SCHEMBL18561861 0.82 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL18297186 0.82 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL7055868 0.82 TSHR (0.39) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL17297567 0.81 TSHR (0.36) TSHRHPGDTHRBALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112980549-B High viscosity index comb polymer viscosity modifiers and methods of using the same to alter lubricant viscosity 英菲诺姆国际有限公司 2023-12-15 CN disclosed
EP-3839018-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-10-18 EP disclosed
EP-3839019-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-08-02 EP disclosed
US-11685874-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2023-06-27 US disclosed
US-11384311-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-07-12 US disclosed
US-11365273-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-21 US disclosed
US-20220169947-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-02 US disclosed
US-20210189281-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same lnfineum International Limited (GB) 2021-06-24 US disclosed
EP-3839018-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
EP-3839019-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
EP-3839017-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
US-20210179760-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179960-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modify Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179961-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179965-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-8182695-B2 Bridged macrocyclic module compositions WHITEFORD JEFFERY A (US) 2012-05-22 US disclosed
US-20080290034-A1 Bridged macrocyclic module compositions COVALENT PARTNERS LLC 2008-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080290034-A1 Bridged macrocyclic module compositions SBDS, NCL, INTS6 TSHR 4746/4885HPGD 2178/4885THRB 4874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.