SCHEMBL678325

SCHEMBL678325

CC(C)([SbH2])c1ccccn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CHRM2 P08172 2/20 0.41
KDM4E B2RXH2 3/20 0.40
BLM P54132 2/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.40
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
METAP1 P53582 1/20 0.40
HIF1A Q16665 1/20 0.40
DOHH Q9BU89 1/20 0.40
P4HTM Q9NXG6 1/20 0.40
AHR P35869 1/20 0.38
TDP1 Q9NUW8 3/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349628 0.80 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM
SCHEMBL31645911 0.80 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM
SCHEMBL28883610 0.80 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM
SCHEMBL29080 0.80 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM
SCHEMBL10356935 0.80 SMN1; SMN2 (0.58) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM
SCHEMBL7454285 0.79 SMN1; SMN2 (0.52) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM
Iodide SCHEMBL2177798 0.78 SMN1; SMN2 (0.56) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM
SCHEMBL29798224 0.78 SMN1; SMN2 (0.56) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM
SCHEMBL29016490 0.78 SMN1; SMN2 (0.56) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM
Ammonia Solution, Strong SCHEMBL7412270 0.78 SMN1; SMN2 (0.56) SMN1; SMN2L3MBTL1CHRM2KDM4EBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
US-8008414-B2 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
EP-1767539-A1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL COMPANY, LTD. (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer AOC2, ODC1, MCM7 SMN1; SMN2 2499/4885L3MBTL1 314/4885CHRM2 66/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.