Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6784418 | 0.99 | KCNH2 (0.47) | KCNH2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6789851 | 0.95 | SIGMAR1 (0.46) | KMT2AMEN1ALDH1A1LMNALTA4H | |
| Hydrochloric Acid SCHEMBL6786107 | 0.94 | SIGMAR1 (0.45) | KCNH2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6783426 | 0.91 | SIGMAR1 (0.46) | KMT2AMEN1ALDH1A1LMNATHRB | |
| SCHEMBL6785318 | 0.91 | MMP1 (0.49) | KMT2AMEN1ALDH1A1LMNALTA4H | |
| Hydrochloric Acid SCHEMBL6782777 | 0.90 | SIGMAR1 (0.45) | KMT2AMEN1ALDH1A1LMNATHRB | |
| SCHEMBL6791086 | 0.90 | HTR2A (0.43) | KCNH2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6783586 | 0.90 | MMP1 (0.50) | KMT2AMEN1ALDH1A1LMNAHRH3 | |
| Hydrochloric Acid SCHEMBL6780001 | 0.90 | MMP1 (0.48) | KMT2AMEN1ALDH1A1LMNALTA4H | |
| Hydrochloric Acid SCHEMBL6785753 | 0.89 | HTR2A (0.42) | KCNH2KMT2AMEN1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710060-B2 | 4-hydroxypiperidine derivatives having antiarrhythmic activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-23 | — | — | US | disclosed |
| US-20020188006-A1 | 4-hydroxypiperidine derivatives having antiarrhythmic activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-12 | — | — | US | disclosed |
| EP-1182192-A1 | 4-HYDROXYPIPERIDINE DERIVATIVES HAVING ANTIARRHYTHMIC EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020188006-A1 | 4-hydroxypiperidine derivatives having antiarrhythmic activity | SCN5A, RYR2, SCN1B | KCNH2 6/4885KMT2A 2156/4885MEN1 4123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.