⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878346 | 0.73 | — | — | |
| SCHEMBL17552593 | 0.72 | — | — | |
| SCHEMBL2977336 | 0.72 | — | — | |
| SCHEMBL87230 | 0.72 | — | — | |
| SCHEMBL19682787 | 0.70 | ACHE (0.31) | — | |
| SCHEMBL28975534 | 0.70 | RAPGEF4 (0.31) | — | |
| SCHEMBL11095834 | 0.69 | — | — | |
| SCHEMBL12108326 | 0.69 | — | — | |
| SCHEMBL12912878 | 0.69 | — | — | |
| SCHEMBL2036439 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812406-B1 | NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA NV (BE) | 2018-09-12 | — | — | EP | disclosed |
| CN-102639529-B | Isoxazoline derivative-based pesticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-19 | — | — | CN | disclosed |
| US-8586616-B2 | Benzimidazole derivatives useful as selective androgen receptor modulators (SARMS) | JANSSEN PHARMACEUTICA, NV (BE) | 2013-11-19 | — | — | US | disclosed |
| EP-1619211-B1 | PROCESS FOR PRODUCTION OF LIVING-RADICAL POLYMERS AND POLYMERS | OTSUKA CHEMICAL CO LTD (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-20110275774-A1 | ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER | YAMAGO SHIGERU | 2011-11-10 | — | — | US | disclosed |
| EP-1595894-B1 | PROCESS FOR THE PRODUCTION OF LIVING RADICAL POLYMERS | OTSUKA CHEMICAL CO LTD (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-8008414-B2 | Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| EP-1767539-B1 | ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER | OTSUKA CHEMICAL CO LTD (JP) | 2011-07-27 | — | — | EP | disclosed |
| US-20110086883-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | NG RAYMOND | 2011-04-14 | — | — | US | disclosed |
| US-7879895-B2 | prepared by mixing 1-(5,6-dichloro-1H-benzimidazol-2-yl)-2,2,2-trifluoro-ethanol with a carrier; non-steroidal agonists and antagonists; anticarcinogenic agents prostates; alopecia; eating disorders; acne; AIDS; cachexia | JANSSEN PHARMACEUTICA NV (BE) | 2011-02-01 | — | — | US | disclosed |
| US-20060199927-A1 | Process for production of living-radical polymers and polymers | Outdoor Wireless Networks LLC | 2006-09-07 | — | — | US | disclosed |
| US-20060167199-A1 | Process for produciton of living radical polymers and polymers | OTSUKA CHEMICAL CO., LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060135711-A1 | Process for the production of living radical polymers and polymers | OTSUKA CHEMICAL CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |
| US-20060116412-A1 | Novel benzimidazole derivatives useful as selective androgen receptor modulators (sarms) | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-01 | — | — | US | disclosed |
| US-20060111402-A1 | Novel benzimidazole derivatives useful as selective androgen receptor modulators (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-25 | — | — | US | disclosed |
| WO-2006039215-A2 | NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-04-13 | — | — | WO | disclosed |
| WO-2006039243-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES USEFUL AS SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-04-13 | — | — | WO | disclosed |
| EP-1619211-A1 | PROCESS FOR PRODUCTION OF LIVING-RADICAL POLYMERS AND POLYMERS | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2006-01-25 | — | — | EP | disclosed |
| EP-1595894-A1 | PROCESS FOR THE PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2005-11-16 | — | — | EP | disclosed |
| EP-1541592-A1 | PROCESS FOR PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2005-06-15 | — | — | EP | disclosed |