Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | IL4I1 | Q96RQ9 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312189 | 0.76 | CYP2A6 (0.61) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL7287505 | 0.74 | L3MBTL1 (0.58) | MAPTCYP11B1CYP11B2ALDH1A1TSHR | |
| SCHEMBL30948248 | 0.73 | IL4I1 (0.48) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| Hydrochloric Acid SCHEMBL5578157 | 0.72 | L3MBTL1 (0.56) | MAPTCYP11B1CYP11B2ALDH1A1TSHR | |
| SCHEMBL2121672 | 0.72 | CYP2A6 (1.00) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL2305968 | 0.72 | CYP2A6 (0.72) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL27163520 | 0.72 | CYP2A6 (0.72) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL10162470 | 0.72 | CYP2A6 (0.72) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL13616481 | 0.71 | CYP2A6 (0.52) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 | |
| Hydrochloric Acid SCHEMBL3606661 | 0.71 | CYP2A6 (0.97) | CYP2E1CYP2A6CYP2C9CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759419-B2 | NOOTROPIC AGENTS; BRAIN DISORDERS; ALZHEIMER'S DISEASE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-07-06 | — | — | US | claimed |
| US-20030114491-A1 | Pyrrolidinone derivatives, their preparation and pharmaceutical composition comprising the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-19 | — | — | US | claimed |
| US-6759419-B2 | NOOTROPIC AGENTS; BRAIN DISORDERS; ALZHEIMER'S DISEASE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-07-06 | — | — | US | disclosed |
| US-20030114491-A1 | Pyrrolidinone derivatives, their preparation and pharmaceutical composition comprising the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114491-A1 | Pyrrolidinone derivatives, their preparation and pharmaceutical composition comprising the same | CHRM1, CHRNA5, CHRNA7 | CYP2E1 1178/4885CYP2A6 503/4885CYP2C9 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.