Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31287661 | 0.81 | LMNA (0.44) | LMNACES2TSHRGABRR1TLR4 | |
| SCHEMBL18804450 | 0.79 | LMNA (0.36) | LMNACES2TSHRGABRR1 | |
| SCHEMBL9231482 | 0.79 | LMNA (0.47) | LMNACES2TSHRGABRR1 | |
| SCHEMBL17613472 | 0.75 | LMNA (0.47) | LMNACES2TSHR | |
| SCHEMBL9392982 | 0.75 | CES2 (0.47) | LMNACES2TSHR | |
| SCHEMBL10622106 | 0.72 | — | — | |
| SCHEMBL7736279 | 0.71 | LMNA (0.34) | LMNACES2TSHR | |
| SCHEMBL2404760 | 0.71 | — | — | |
| SCHEMBL15241732 | 0.65 | — | — | |
| SCHEMBL2559392 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809101-B2 | RNA POLYMERASES INHIBITORS; SUCH AS 5-(1-HYDROXY-1-(5-METHYL-OXAZOL-2-YL))METHYLENE-2-THIOXOTHIAZOLIDIN-4-ONE | SHIONOGI & CO., LTD. (JP) | 2004-10-26 | — | — | US | disclosed |
| US-20030203948-A1 | Compounds having anti-hepatitics c virus effect | Z-KAT, INC. | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203948-A1 | Compounds having anti-hepatitics c virus effect | NSUN3, HCCS, NSUN2 | LMNA 3879/4885CES2 397/4885TSHR 2415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.