⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796174 | 0.75 | — | — | |
| SCHEMBL9796178 | 0.75 | — | — | |
| SCHEMBL15870907 | 0.72 | MEN1 (0.45) | — | |
| SCHEMBL6158176 | 0.71 | — | — | |
| SCHEMBL25402819 | 0.69 | — | — | |
| SCHEMBL737125 | 0.69 | — | — | |
| SCHEMBL25403025 | 0.68 | — | — | |
| Iodomethane SCHEMBL27703487 | 0.68 | FGF23 (0.38) | — | |
| SCHEMBL3855234 | 0.67 | — | — | |
| SCHEMBL25401247 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3133 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024022481-A1 | PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUNDS, AND PREPARATION AND USE THEREOF | 苏中药业集团股份有限公司 | 2024-02-01 | — | — | WO | claimed |
| US-20220135557-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-05-05 | — | — | US | claimed |
| US-20220119382-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-04-21 | — | — | US | claimed |
| US-11242345-B2 | Sulfonimidoylpurinone compounds and methods of treatment using the same | HOFFMANN-LA ROCHE INC. (US) | 2022-02-08 | — | — | US | claimed |
| EP-3894396-A1 | 2-OXOQUINAZOLINE DERIVATIVES AS METHIONINE ADENOSYLTRANSFERASE 2A INHIBITORS | Ideaya Biosciences, Inc. (US) | 2021-10-20 | — | — | EP | claimed |
| EP-3891149-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2021-10-13 | — | — | EP | claimed |
| EP-3891148-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2021-10-13 | — | — | EP | claimed |
| US-20210206760-A1 | PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUND AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2021-07-08 | — | — | US | claimed |
| WO-2021136326-A1 | ARYL AMIDE COMPOUND AND APPLICATION THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2021-07-08 | — | — | WO | claimed |
| EP-3798219-A1 | PHENYL-SUBSTITUTED DIHYDRONAPHTHYRIDINE COMPOUND AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2021-03-31 | — | — | EP | claimed |
| EP-1347957-A1 | DELTA 1-PYRROLINES USED AS PESTICIDES | Bayer CropScience AG (DE) | 2003-10-01 | — | — | EP | claimed |
| US-20030100548-A1 | Arylpiperazines and their use as metallaproteinase inhibiting agents (mmp) | ASTRAZENECA AB (SE) | 2003-05-29 | — | — | US | claimed |
| EP-1274697-A1 | ARYLPIPERAZINES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS (MMP) | AstraZeneca AB (SE) | 2003-01-15 | — | — | EP | claimed |
| WO-2002067684-A1 | PYRIDYL PYRIMIDINES FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-09-06 | — | — | WO | claimed |
| WO-2002046151-A1 | DELTA 1-PYRROLINES USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2002-06-13 | — | — | WO | claimed |
| WO-2002006244-A1 | HETEROCYCLIC SUBSTITUTED HERBICIDAL SULPHONIC ACID ANILIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-24 | — | — | WO | claimed |
| WO-2002006277-A1 | SUBSTITUTED BENZO-NITRO-HETEROCYCLES AND USE THEREOF AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-24 | — | — | WO | claimed |
| WO-2001062750-A1 | ARYLPIPERAZINES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS (MMP) | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | claimed |
| EP-0571822-B1 | Diazabicycloalkene derivatives | DAIICHI SEIYAKU CO (JP) | 2001-08-16 | — | — | EP | claimed |
| US-5418232-A | Hypotensive, increases renal blood flow | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-05-23 | — | — | US | claimed |