Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5718172 | 1.00 | MEN1 (0.34) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL20468466 | 0.69 | ATM (0.32) | MEN1KMT2APOLBOPRM1SLC22A1 | |
| SCHEMBL6617476 | 0.69 | CTDSP1 (0.36) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL20465367 | 0.68 | SLC22A1 (0.32) | MEN1KMT2APOLBALDH1A1SLC22A1 | |
| SCHEMBL19968798 | 0.67 | NFKB1 (0.35) | POLBSMN1; SMN2 | |
| SCHEMBL4926717 | 0.66 | ATM (0.37) | MEN1KMT2APOLBALDH1A1L3MBTL1 | |
| SCHEMBL38663307 | 0.66 | SMN1; SMN2 (0.32) | OPRM1SLC22A1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL20021553 | 0.66 | OPRM1 (0.32) | OPRM1OPRD1OPRK1ATM | |
| SCHEMBL6161155 | 0.66 | OPRM1 (0.35) | MEN1KMT2APOLBOPRM1SLC22A1 | |
| SCHEMBL18482794 | 0.65 | MEN1 (0.32) | MEN1KMT2APOLBOPRM1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790964-B1 | HYDROXY OR ALKOXY IN THE 5-POSITION; DECYCLIZATION OF A 5-HYDROXY-7- OXABICYCLO(4.1.0)HEPT-2-ENE-3-CARBOXYLATE WITH AN AMINE TO GIVE AMINODIOL, SULFONYLATING, REACTION WITH ALCOHOL; | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2004-09-14 | — | — | US | disclosed |