Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 8/20 | 0.42 |
| ▸ | F10 | P00742 | 7/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | PLG | P00747 | 3/20 | 0.38 |
| ▸ | PLAU | P00749 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.37 |
| ▸ | KLK8 | O60259 | 1/20 | 0.37 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6785474 | 0.99 | KIF11 (0.43) | KIF11PARP1F2F10PRSS1 | |
| SCHEMBL6788106 | 0.88 | NR4A2 (0.41) | KIF11PARP1F2F10NR4A2 | |
| Hydrochloric Acid SCHEMBL6788097 | 0.87 | NR4A2 (0.40) | KIF11PARP1F2F10NR4A2 | |
| SCHEMBL6786964 | 0.85 | KIF11 (0.45) | KIF11PARP1F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL6786963 | 0.84 | KIF11 (0.44) | KIF11PARP1F2F10PRSS1 | |
| SCHEMBL6788527 | 0.82 | KIF11 (0.46) | KIF11PARP1F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL6788523 | 0.82 | KIF11 (0.46) | KIF11PARP1F2F10PRSS1 | |
| SCHEMBL6793456 | 0.80 | HTT (0.45) | F2F10PRSS1 | |
| Hydrochloric Acid SCHEMBL6793449 | 0.79 | HTT (0.44) | F2F10PRSS1 | |
| SCHEMBL6791284 | 0.76 | F2 (0.39) | KIF11F2F10PRSS1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699862-B1 | ANTITUMOR | PFIZER INC. | 2004-03-02 | — | — | US | claimed |