Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31186332 | 0.86 | ALDH1A1 (0.58) | HCAR2LMNAALDH1A1FNTAFNTB | |
| SCHEMBL6553346 | 0.81 | HCAR2 (0.43) | HCAR2LMNAALDH1A1FNTAFNTB | |
| SCHEMBL4892609 | 0.81 | HCAR2 (0.43) | HCAR2LMNAALDH1A1FNTAFNTB | |
| SCHEMBL1630557 | 0.81 | TSHR (0.38) | ALDH1A1TSHR | |
| SCHEMBL6786515 | 0.80 | ALDH1A1 (0.50) | HCAR2LMNAALDH1A1FNTAFNTB | |
| SCHEMBL7772523 | 0.79 | HCAR2 (0.42) | HCAR2LMNAALDH1A1FNTAFNTB | |
| SCHEMBL7771313 | 0.79 | HCAR2 (0.42) | HCAR2LMNAALDH1A1FNTAFNTB | |
| SCHEMBL6877096 | 0.79 | HCAR2 (0.42) | HCAR2LMNAALDH1A1FNTAFNTB | |
| SCHEMBL9757786 | 0.78 | HCAR2 (0.45) | HCAR2LMNAALDH1A1TSHRESR1 | |
| SCHEMBL7758324 | 0.77 | HCAR2 (0.41) | HCAR2LMNAALDH1A1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259992-A1 | Two-component adhesion promoter combination of an unsaturated alkoxysilane and a mercaptoalkyl alkoxysilane, for use in dental prostheses | 3M ESPE AG (DE) | 2004-12-23 | — | — | US | disclosed |
| US-6833425-B1 | Filler for plastic formulations based on polyurethane | 3M ESPE AG (DE) | 2004-12-21 | — | — | US | disclosed |
| US-6767935-B1 | CATIONIC POLYMERIZATION OF UNSATURATED CARBONIC ACIDS, ANHYDRIDES OR ACID CHLORIDES, PHOSPHORIC OR PHOSPHONIC ACID OR ESTERS, SULFONIC ACIDS OR ESTERS; CURING | 3M ESPE AG (DE) | 2004-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259992-A1 | Two-component adhesion promoter combination of an unsaturated alkoxysilane and a mercaptoalkyl alkoxysilane, for use in dental prostheses | ITGA2, ITGB2, ITGA2B | HCAR2 599/4885LMNA 4232/4885ALDH1A1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.