Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8270009 | 0.73 | HDAC8 (0.45) | TSHRTTRALBCYP2A6ALDH1A1 | |
| SCHEMBL667047 | 0.69 | TSHR (0.57) | TSHRALDH1A1KDM4E | |
| SCHEMBL60145 | 0.67 | TTR (0.50) | TSHRTTRALBCYP2A6ALDH1A1 | |
| SCHEMBL501406 | 0.67 | ALDH1A1 (0.52) | TSHRTTRALBCYP2A6ALDH1A1 | |
| SCHEMBL1004620 | 0.67 | ALDH1A1 (0.52) | TSHRTTRALBCYP2A6ALDH1A1 | |
| SCHEMBL2884807 | 0.65 | HDAC8 (0.45) | TSHRCYP2A6ALDH1A1HDAC8KDM4E | |
| SCHEMBL8240148 | 0.65 | TSHR (0.52) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL898962 | 0.65 | TSHR (0.52) | TSHRALDH1A1KDM4E | |
| SCHEMBL2153449 | 0.65 | TTR (0.44) | TSHRTTRALBCYP2A6ALDH1A1 | |
| SCHEMBL6550332 | 0.65 | TSHR (0.52) | TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116480-A1 | Oxime ether compound and agricultural or horticultural bactericide | NIPPON SODA CO., LTD. (JP) | 2004-06-17 | — | — | US | disclosed |
| EP-1362850-A1 | OXIME ETHER COMPOUND AND AGRICULTURAL OR HORTICULTURAL BACTERICIDE | NIPPON SODA CO., LTD. (JP) | 2003-11-19 | — | — | EP | disclosed |