Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | SELE | P16581 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1004620 | 0.94 | ALDH1A1 (0.52) | ALDH1A1CYP2A6TTRALBGRM5 | |
| SCHEMBL29791324 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CYP2A6TTRALBGRM5 | |
| SCHEMBL1639085 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CYP2A6TTRALBGRM5 | |
| SCHEMBL6741465 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TTRALBGRM5 | |
| SCHEMBL2160734 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TTRALBGRM5 | |
| SCHEMBL254589 | 0.82 | TTR (0.43) | ALDH1A1CYP2A6TTRALBGRM5 | |
| SCHEMBL16962561 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TTRALBGRM5 | |
| SCHEMBL18934332 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TTRALBGRM5 | |
| SCHEMBL3258882 | 0.82 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TTRALBGRM5 | |
| SCHEMBL255241 | 0.82 | GRM5 (0.45) | ALDH1A1CYP2A6TTRALBGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12485121-B2 | Antiviral agents for the treatment and prevention of HIV infection | PHARMASYNTEZ, JOINT STOCK COMPANY (RU) | 2025-12-02 | — | — | US | claimed |
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | claimed |
| CN-113720926-B | Method for detecting impurity content in itraconazole intermediate 1 | 浙江致新医药科技有限公司 | 2023-05-09 | — | — | CN | claimed |
| US-20230120294-A1 | ANTIVIRAL AGENTS FOR THE TREATMENT AND PREVENTION OF HIV INFECTION | PHARMASYNTEZ, JOINT STOCK COMPANY (RU) | 2023-04-20 | — | — | US | claimed |
| EP-4107156-A1 | PYRIMIDINE-BASED BICYCLES AS ANTIVIRAL AGENTS FOR THE TREATMENT AND PREVENTION OF HIV INFECTION | Joint Stock Company "Pharmasyntez" (RU) | 2022-12-28 | — | — | EP | claimed |
| CN-115279757-A | Pyrimidine bicyclic compounds as antiviral agents for the treatment and prevention of HIV infection | 法玛西泰股份公司 | 2022-11-01 | — | — | CN | claimed |
| US-20220242847-A1 | PYRIDINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS | MERCK SHARP & DOHME CORP. (US) | 2022-08-04 | — | — | US | claimed |
| US-20220064147-A1 | PYRIMIDONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS | MERCK SHARP & DOHME CORP. (US) | 2022-03-03 | — | — | US | claimed |
| US-20260071247-A1 | PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH | TETS VICTOR (US) | 2026-03-12 | — | — | US | disclosed |
| US-20260071248-A1 | PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH | TETS VICTOR (US) | 2026-03-12 | — | — | US | disclosed |
| US-20260071249-A1 | PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH | TETS VICTOR (US) | 2026-03-12 | — | — | US | disclosed |
| US-12485121-B2 | Antiviral agents for the treatment and prevention of HIV infection | PHARMASYNTEZ, JOINT STOCK COMPANY (RU) | 2025-12-02 | — | — | US | disclosed |
| WO-2025245178-A1 | PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | INNOVO THERAPEUTICS, INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| WO-2025202185-A1 | PROCESS FOR THE FUNCTIONALIZATION OF AN AROMATIC OR HETEROAROMATIC AMINO COMPOUND | STUDIENGESELLSCHAFT KOHLE GGMBH (DE) | 2025-10-02 | — | — | WO | disclosed |
| US-20030065187-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-03 | — | — | US | disclosed |
| WO-2002085838-A1 | COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-31 | — | — | WO | disclosed |
| EP-1151990-A1 | Substituted N-arylmethylamino derivatives of cyclobutene-3, 4-diones | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0934257-A1 | SUBSTITUTED N-ARYLMETHYLAMINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| US-5780505-A | ADMINISTERING AS SMOOTH MUSCLE RELAXANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998002413-A1 | SUBSTITUTED N-ARYLMETHYLAMINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064147-A1 | PYRIMIDONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS | TYMP, PNP, CD4 | ALDH1A1 2371/4885CYP2A6 3117/4885TTR 2015/4885 |
| US-20260071248-A1 | PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH | C1S, C5, EIF6 | ALDH1A1 4194/4885CYP2A6 1687/4885TTR 3200/4885 |
| US-20260071249-A1 | PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH | EIF2A, EIF6, TUFM | ALDH1A1 4636/4885CYP2A6 4244/4885TTR 1563/4885 |
| US-20030065187-A1 | Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds | ADH5, CBR3, ALDH3A1 | ALDH1A1 26/4885CYP2A6 90/4885TTR 1583/4885 |
| US-12485121-B2 | Antiviral agents for the treatment and prevention of HIV infection | TYMP, TYMS, UMPS | ALDH1A1 2749/4885CYP2A6 2172/4885TTR 3140/4885 |
| US-20220242847-A1 | PYRIDINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS | PRUNE1, G6PD, ACIN1 | ALDH1A1 1817/4885CYP2A6 1622/4885TTR 3580/4885 |
| US-20260071247-A1 | PRODUCTS FOR REGULATION OF EUKARYOTIC AND MICROBIAL CELLS GROWTH | AMPD1, TUFM, AMPD3 | ALDH1A1 4680/4885CYP2A6 3955/4885TTR 1410/4885 |
| US-20230120294-A1 | ANTIVIRAL AGENTS FOR THE TREATMENT AND PREVENTION OF HIV INFECTION | TYMP, TYMS, UMPS | ALDH1A1 2749/4885CYP2A6 2172/4885TTR 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.