Sugi Predict

Sugi Predict / Compounds / SCHEMBL678640

SCHEMBL678640

SCHEMBL678640

c1ccc(-n2nnc3ccccc32)nc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 3/20 1.00
▸ POLB P06746 2/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ KCNMA1 Q12791 1/20 0.50
▸ TSHR P16473 1/20 0.50
▸ NPC1 O15118 1/20 0.49
▸ CCNE1 P24864 4/20 0.47
▸ CDK2 P24941 4/20 0.47
▸ MAPK8 P45983 4/20 0.47
▸ MAPK9 P45984 4/20 0.47
▸ ALDH1A1 P00352 4/20 0.46
▸ CYP2C9 P11712 3/20 0.46
▸ SLC9A1 P19634 3/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ KEAP1 Q14145 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ CYP2D6 P10635 1/20 0.46
▸ MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30355239 1.00 RAB9A (1.00) RAB9APOLBSMN1; SMN2KCNMA1TSHR
SCHEMBL16036700 0.83 RAB9A (0.71) RAB9APOLBSMN1; SMN2KCNMA1TSHR
SCHEMBL16796215 0.81 RAB9A (0.68) RAB9APOLBSMN1; SMN2KCNMA1TSHR
SCHEMBL23619041 0.80 RAB9A (0.67) RAB9APOLBSMN1; SMN2KCNMA1TSHR
SCHEMBL6301937 0.78 RAB9A (0.64) RAB9APOLBSMN1; SMN2TSHRNPC1
SCHEMBL20156597 0.76 RAB9A (0.61) RAB9APOLBSMN1; SMN2KCNMA1TSHR
SCHEMBL11612094 0.76 RAB9A (0.61) RAB9APOLBSMN1; SMN2KCNMA1TSHR
SCHEMBL12175465 0.76 RAB9A (0.61) RAB9APOLBSMN1; SMN2KCNMA1TSHR
SCHEMBL16035881 0.76 RAB9A (0.60) RAB9APOLBSMN1; SMN2TSHRNPC1
SCHEMBL15430860 0.75 RAB9A (0.58) RAB9APOLBSMN1; SMN2TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861256-A Preparation method and application of 16, 17-dihydroxysteroid compound 天津药业研究院股份有限公司 2021-12-31 — — CN claimed
US-20230305403-A1 PATTERN FORMING METHOD, MANUFACTURING METHOD OF CIRCUIT BOARD, AND LAMINATE FUJIFILM CORPORATION (JP) 2023-09-28 — — US disclosed
CN-116194845-A Photomask, exposure method, method for producing resin pattern, and method for producing photomask 富士胶片株式会社 2023-05-30 — — CN disclosed
WO-2023090253-A1 LAMINATE, METHOD FOR PRODUCING SAME, AND ELECTRONIC DEVICE 富士フイルム株式会社 2023-05-25 — — WO disclosed
CN-116149141-A Method for producing resin pattern, method for producing conductive pattern, and laminate 富士胶片株式会社 2023-05-23 — — CN disclosed
CN-116149136-A Photosensitive composition, laminate, pattern forming method, and patterned laminate 富士胶片株式会社 2023-05-23 — — CN disclosed
CN-116149134-A Method for producing resin pattern, method for producing conductive pattern, and laminate 富士胶片株式会社 2023-05-23 — — CN disclosed
CN-115668061-A Pattern forming method, circuit board manufacturing method, and laminate 富士胶片株式会社 2023-01-31 — — CN disclosed
US-11325908-B2 CaMKII inhibitors and uses thereof THE JOHNS HOPKINS UNIVERSITY (US) 2022-05-10 — — US disclosed
US-11325908-B2 CaMKII inhibitors and uses thereof THE JOHNS HOPKINS UNIVERSITY (US) 2022-05-10 — — US disclosed
US-20160024078-A1 CaMKII INHIBITORS AND USES THEREOF ALLOSTEROS THERAPEUTICS, INC. (US) 2016-01-28 — — US disclosed
US-20160024078-A1 CaMKII INHIBITORS AND USES THEREOF ALLOSTEROS THERAPEUTICS, INC. (US) 2016-01-28 — — US disclosed
US-8895744-B2 Alfa-carboline inhibitors of NPM-ALK, RET, and Bcr-Abl UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA (IT) 2014-11-25 — — US disclosed
WO-2014138212-A1 CaMKII INHIBITORS AND USES THEREOF ALLOSTEROS THERAPEUTICS, INC. (US) 2014-09-12 — — WO disclosed
US-20110281862-A1 ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL UNIVERSITA' DEGLI STUDI DI MILANO - BICOCCA (IT) 2011-11-17 — — US disclosed
WO-2011139242-A2 PROCESS FOR THE PREPARATION OF 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE DERIVATIVES USTAV EXPIREMENTÁLNEJ FARMAKOLÓGIE A TOXIKOLÓGIE SAV (SK) 2011-11-10 — — WO disclosed
CN-1067061-C Herbicidal substituted 1-phenyl or 1-pyridinyl-benzotriazoles ZENECA LTD (GB) 2001-06-13 — — CN disclosed
CN-1067061-C Herbicidal substituted 1-phenyl or 1-pyridinyl-benzotriazoles ZENECA LTD (GB) 2001-06-13 — — CN disclosed
CN-1124959-A Herbicidal substituted 1-phenyl or 1-pyridyl benzotriazoles ZENECA LTD (GB) 1996-06-19 — — CN disclosed
CN-1124959-A Herbicidal substituted 1-phenyl or 1-pyridyl benzotriazoles ZENECA LTD (GB) 1996-06-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11325908-B2 CaMKII inhibitors and uses thereof CAMK2G, CAMK2B, CAMK1 RAB9A 3402/4885POLB 3430/4885SMN1; SMN2 3977/4885
US-20110281862-A1 ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL ALK, BCR, NPM1 RAB9A 2539/4885POLB 2689/4885SMN1; SMN2 3499/4885
US-20160024078-A1 CaMKII INHIBITORS AND USES THEREOF CAMK2G, CAMK2B, CAMK1 RAB9A 3402/4885POLB 3430/4885SMN1; SMN2 3977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.