SCHEMBL678682

SCHEMBL678682

COC(=O)CC(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30876013 0.81
SCHEMBL1523144 0.78 TSHR (0.48)
SCHEMBL28355267 0.77
SCHEMBL11140368 0.77 TSHR (0.42)
SCHEMBL27607036 0.77 TSHR (0.42)
SCHEMBL1634880 0.77 ALDH1A1 (0.35)
SCHEMBL5692424 0.76 TSHR (0.46)
SCHEMBL18334512 0.76 TSHR (0.46)
SCHEMBL10482256 0.76 TSHR (0.46)
SCHEMBL9327767 0.75 TSHR (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110903183-A Novel preparation method of 3,3, 3-trifluoropropionic acid 湖南有色郴州氟化学有限公司 2020-03-24 CN claimed
CN-110123865-A Composition comprising man and wife's grass extract 嘉兴市爵拓科技有限公司 2019-08-16 CN claimed
CN-106930745-A Exploitation of oil-gas field method 北京仁创科技集团有限公司 2017-07-07 CN claimed
CN-104948158-A Hydraulic fracturing oil and gas field exploitation method BEIJING RECHSAND SCI & TECH GR 2015-09-30 CN claimed
CN-104944840-A Preparation method of self-suspension proppant for natural hydrofracturing construction BEIJING RECHSAND SCI & TECH GR 2015-09-30 CN claimed
CN-101711762-A Medicine composition for treating hypertension LUNAN PHARM GROUP CORP 2010-05-26 CN claimed
US-20240226128-A1 NOVEL COMPOUNDS WITH DUAL INHIBITION ACTIVITY AGAINST SARS-COV-2 CRITICAL ENZYMES RDRP, MPRO AND HUMAN TMPRSS2 UNIVERSITY OF SHARJAH (AE) 2024-07-11 US disclosed
WO-2023160004-A1 FUSED-RING COMPOUND HAVING ANALGESIC ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 南京知和医药科技有限公司 2023-08-31 WO disclosed
CN-110257468-B Composition for quality control of bacterial counting, preparation method and application thereof 北京鑫骥金诺医疗器械有限公司 2022-05-27 CN disclosed
CN-113930442-A Materials and methods for producing PUFAs and compositions containing PUFAs 巴斯夫植物科学有限公司 2022-01-14 CN disclosed
CN-110903183-A Novel preparation method of 3,3, 3-trifluoropropionic acid 湖南有色郴州氟化学有限公司 2020-03-24 CN disclosed
CN-110257468-A A kind of composition of the Quality Control for count of bacteria, preparation method and applications 北京鑫骥金诺医疗器械有限公司 2019-09-20 CN disclosed
CN-110123865-A Composition comprising man and wife's grass extract 嘉兴市爵拓科技有限公司 2019-08-16 CN disclosed
EP-0135351-A1 Manufacturing process for N-carbobenzyloxy-L-glutamic acid-alpha-cholinester salt MORINAGA MILK INDUSTRY CO., LTD. (JP) 1985-03-27 EP disclosed
EP-0134782-A4 PROCESS FOR THE PREPARATION OF 3-AMINO-5-HYDROXYBENZOIC ACIDS AND DERIVATIVES AND ANALOGUES THEREOF. UNIV AUSTRALIAN (AU) 1985-02-18 EP disclosed
WO-1984000750-A1 PROCESS FOR THE PREPARATION OF 3-AMINO-5-HYDROXYBENZOIC ACIDS AND DERIVATIVES AND ANALOGUES THEREOF UNIV AUSTRALIAN (AU) 1984-03-01 WO disclosed
US-4396607-A IMMUNOLOGY, ANTIGENS AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1983-08-02 US disclosed
US-4284619-A INJECTING RADIOIODINE COMPOUND MEDI-PHYSICS, INC. (US) 1981-08-18 US disclosed
US-4279887-A RADIOACTIVE SCANNING MEDI-PHYSICS, INC. (US) 1981-07-21 US disclosed
US-4251520-A ANTIPYRETIC AND ANTIINFLAMMATORY AGENTS SPA-SOCIETA PRODOTTI ANTIBIOTICI S.P.A. (IT) 1981-02-17 US disclosed