Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5274829 | 0.89 | CA1 (0.31) | — | |
| SCHEMBL11526564 | 0.89 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL1634881 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL374737 | 0.79 | — | — | |
| SCHEMBL23132669 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL678682 | 0.77 | — | — | |
| SCHEMBL27627850 | 0.77 | — | — | |
| SCHEMBL11124619 | 0.77 | — | — | |
| SCHEMBL27568817 | 0.77 | — | — | |
| SCHEMBL27667850 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102507705-A | Method for determining agomelatine content | CHENGDU XINJIE HI TECH DEV CO LTD | 2012-06-20 | — | — | CN | claimed |
| JP-58025325-A | — | — | None | — | — | JP | disclosed |
| US-8518992-B2 | Method of synthesis and purification of N-6-trimethyl-L-lysine and derivative compounds | CHEMGENES CORPORATION | 2013-08-27 | — | — | US | disclosed |
| CN-102507705-A | Method for determining agomelatine content | CHENGDU XINJIE HI TECH DEV CO LTD | 2012-06-20 | — | — | CN | disclosed |
| CN-102507705-A | Method for determining agomelatine content | CHENGDU XINJIE HI TECH DEV CO LTD | 2012-06-20 | — | — | CN | disclosed |
| US-20110166379-A1 | Method of synthesis and purification of N-6-Trimethyl-L-Lysine and derivative compounds | CHEMGENES CORPORATION | 2011-07-07 | — | — | US | disclosed |
| US-7932287-B2 | Therapeutic compositions and uses | CHEMGENES CORPORATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20080011438-A1 | CELLULOSIC PRODUCT AND PROCESS FOR ITS PRODUCTION | AKZO NOBEL N.V. (NL) | 2008-01-17 | — | — | US | disclosed |
| US-7303654-B2 | Cellulosic product and process for its production | AKZO NOBEL N.V. (NL) | 2007-12-04 | — | — | US | disclosed |
| US-20060035972-A1 | Therapeutic compositions and uses | CHEMGENES CORPORATION | 2006-02-16 | — | — | US | disclosed |
| EP-1581697-A1 | CELLULOSIC PRODUCT AND PROCESS FOR ITS PRODUCTION | Akzo Nobel N.V. (NL) | 2005-10-05 | — | — | EP | disclosed |
| US-20040140074-A1 | Cellulosic product and process for its production | AKZO NOBEL N.V. (NL) | 2004-07-22 | — | — | US | disclosed |
| WO-2004046464-A1 | CELLULOSIC PRODUCT AND PROCESS FOR ITS PRODUCTION | AKZO NOBEL N.V. (NL) | 2004-06-03 | — | — | WO | disclosed |
| US-5037508-A | Adsorption of pitch in papermaking | J. M. HUBER CORPORATION (US) | 1991-08-06 | — | — | US | disclosed |
| US-4927465-A | ABSORBERS | J. M. HUBER CORPORATION | 1990-05-22 | — | — | US | disclosed |
| WO-1989003863-A1 | CATIONIC CLAYS AND USES IN PAPER AND PAINTS | J.M. HUBER CORPORATION (US) | 1989-05-05 | — | — | WO | disclosed |
| JP-S5825325-A | CURING AGENT FOR EPOXY RESIN | OKAMURA SEIYU KK | 1983-02-15 | — | — | JP | disclosed |
| US-4151199-A | ANTI-THROMBOTIC AGENTS | LILLY INDUSTRIES LIMITED (GB) | 1979-04-24 | — | — | US | disclosed |
| US-4100350-A | 3-Substituted propanoic acid derivatives | LILLY INDUSTRIES LTD. (GB) | 1978-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166379-A1 | Method of synthesis and purification of N-6-Trimethyl-L-Lysine and derivative compounds | CLN6, LCLAT1, LPCAT3 | ALDH1A1 2776/4885TP53 4842/4885TSHR 3743/4885 |
| US-20060035972-A1 | Therapeutic compositions and uses | JMJD6, KDM6A, AADAT | ALDH1A1 674/4885TP53 1547/4885TSHR 3482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.