Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569531 | 0.92 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5569532 | 0.92 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL4645198 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL5570694 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL6785483 | 0.79 | KMT2A (0.51) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL6794084 | 0.78 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL4270404 | 0.77 | KMT2A (0.55) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL4644972 | 0.77 | KMT2A (0.42) | KDM4EKMT2AMEN1 | |
| SCHEMBL6787091 | 0.76 | ATM (0.41) | KDM4EALDH1A1KMT2AMEN1ATM | |
| SCHEMBL6786054 | 0.69 | KDM4E (0.52) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828316-B2 | Antiallergens | KOWA CO., LTD. (JP) | 2004-12-07 | — | — | US | disclosed |
| US-6340682-B1 | FOR THERAPY OF ALLERGIC IMMUNOLOGICAL DISEASE IS SELECTED FROM ASTHMA, ALLERGIC RHINITIS, INFLAMMATORY LARGE BOWEL DISEASE OR CONTACT DERMATITIS | KOWA CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0926138-A1 | DIAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-06-30 | — | — | EP | disclosed |