Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6785483 | 0.96 | KMT2A (0.51) | KMT2AALDH1A1KDM4EHPGDTRPV1 | |
| SCHEMBL4269322 | 0.82 | KDM4E (0.47) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL4269325 | 0.82 | KDM4E (0.47) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL4264302 | 0.80 | HTR1A (0.43) | KMT2AALDH1A1KDM4EHPGDTRPV1 | |
| SCHEMBL6794084 | 0.79 | ALDH1A1 (0.55) | KMT2AALDH1A1KDM4EHPGDTRPV1 | |
| SCHEMBL4279859 | 0.78 | RECQL (0.47) | KMT2AALDH1A1KDM4EHPGDTRPV1 | |
| SCHEMBL4279861 | 0.78 | RECQL (0.47) | KMT2AALDH1A1KDM4EHPGDTRPV1 | |
| SCHEMBL6788079 | 0.77 | KDM4E (0.52) | KMT2AALDH1A1KDM4EHPGDTRPV1 | |
| Pyrrolidine SCHEMBL4268541 | 0.77 | KDM4E (0.43) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 | |
| Pyrrolidine SCHEMBL4268542 | 0.77 | KDM4E (0.43) | KMT2AALDH1A1KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110002-A1 | NOVEL EFFLUX PUMP INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | claimed |