SCHEMBL6788947

SCHEMBL6788947

O=C(CCc1ccc(Br)cc1)N1C(=O)OCC1Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 7/20 0.51
FAAH O00519 3/20 0.41
FKBP1A P62942 1/20 0.40
NPC1 O15118 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
EP300 Q09472 1/20 0.40
CARM1 Q86X55 1/20 0.40
POLB P06746 1/20 0.39
PDPK1 O15530 1/20 0.39
PPARA Q07869 1/20 0.38
LTB4R Q15722 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6334745 0.93 NAAA (0.57) NAAAFAAHFKBP1ANPC1TDP1
SCHEMBL345276 0.93 NAAA (0.57) NAAAFAAHFKBP1ANPC1TDP1
SCHEMBL345275 0.93 NAAA (0.57) NAAAFAAHFKBP1ANPC1TDP1
SCHEMBL2872894 0.89 NAAA (0.52) NAAAFAAHFKBP1ANPC1TDP1
SCHEMBL2872897 0.89 NAAA (0.52) NAAAFAAHFKBP1ANPC1TDP1
SCHEMBL4521529 0.88 NAAA (0.51) NAAAFAAHFKBP1ANPC1TDP1
SCHEMBL22800346 0.88 NAAA (0.51) NAAAFAAHFKBP1ANPC1TDP1
SCHEMBL22800345 0.88 NAAA (0.51) NAAAFAAHFKBP1ANPC1TDP1
SCHEMBL16594226 0.88 NAAA (0.60) NAAAFAAHFKBP1ANPC1TDP1
SCHEMBL16594224 0.88 NAAA (0.60) NAAAFAAHFKBP1ANPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040097499-A1 Amide, carbamate, and urea derivatives ARNOLD MACKLIN BRIAN (US) 2004-05-20 US disclosed
US-6525099-B1 Potentiating glutamate receptor function; psychiatric and neurological disorders ELI LILLY AND COMPANY 2003-02-25 US disclosed
EP-0976744-A1 Amide, carbamate, and urea derivatives having glutamate receptor function potentiating activity ELI LILLY AND COMPANY (US) 2000-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040097499-A1 Amide, carbamate, and urea derivatives GRIN2A, GLUL, GRIK5 NAAA 38/4885FAAH 160/4885FKBP1A 2522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.