Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 2/20 | 0.50 |
| ▸ | TNNT2 | P45379 | 2/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 2/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6789103 | 1.00 | KMT2A (0.50) | KMT2AMEN1MAPTTNNI3TNNT2 | |
| SCHEMBL6790252 | 0.83 | PLCG2 (0.60) | KMT2AMEN1MAPTDAPK3NOTUM | |
| SCHEMBL6790249 | 0.83 | PLCG2 (0.60) | KMT2AMEN1MAPTDAPK3NOTUM | |
| SCHEMBL3585803 | 0.82 | DAPK3 (0.57) | KMT2AMAPTDAPK3MASP2NOTUM | |
| SCHEMBL3585256 | 0.82 | DAPK3 (0.57) | KMT2AMAPTDAPK3MASP2NOTUM | |
| SCHEMBL3585257 | 0.82 | DAPK3 (0.57) | KMT2AMAPTDAPK3MASP2NOTUM | |
| SCHEMBL6796514 | 0.79 | MAPK1 (0.58) | KMT2AMEN1MAPTDAPK3NOTUM | |
| SCHEMBL6796512 | 0.79 | MAPK1 (0.58) | KMT2AMEN1MAPTDAPK3NOTUM | |
| SCHEMBL6797903 | 0.78 | ALDH1A1 (0.53) | KMT2AMEN1MAPTDAPK3NOTUM | |
| SCHEMBL6797901 | 0.78 | ALDH1A1 (0.53) | KMT2AMEN1MAPTDAPK3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | WARNER-LAMBERT COMPANY LLC | 2004-09-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | APP, PSEN1, PSEN2 | KMT2A 4782/4885MEN1 2646/4885MAPT 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.