SCHEMBL6789228

SCHEMBL6789228

CCC(C(=O)O)C(CC)(C(C)=O)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSPD1 P10809 1/20 0.32
BLM P54132 1/20 0.32
HSPE1 P61604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11565066 0.82 SLC1A3 (0.31) HSPD1BLMHSPE1
SCHEMBL11432708 0.77 MEN1 (0.36)
SCHEMBL27561061 0.77
SCHEMBL5257823 0.76 MEN1 (0.30)
SCHEMBL28944444 0.73 CES1 (0.39)
SCHEMBL8747412 0.73
SCHEMBL6630941 0.72 TDP1 (0.37) HSPD1BLMHSPE1
SCHEMBL1201912 0.72 SLC22A6 (0.30)
SCHEMBL28161504 0.72 CHRM1 (0.35)
SCHEMBL1122815 0.71 HSPD1 (0.34) HSPD1BLMHSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0912467-B1 ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE RHODIA CHIMIE SA (FR) 2002-04-24 EP claimed
EP-4578861-A1 NOVEL TRICYCLIC HETEROCYCLIC CARBALDEHYDE COMPOUND AND PHARMACEUTICAL COMPOSITION, CONTAINING SAME, FOR IRE1ALPHA INHIBITION Hanmi Pharm. Co., Ltd. (KR) 2025-07-02 EP disclosed
WO-2024072110-A1 NOVEL TRICYCLIC HETEROCYCLIC CARBALDEHYDE COMPOUND AND PHARMACEUTICAL COMPOSITION, CONTAINING SAME, FOR IRE1α INHIBITION 한미약품 주식회사 2024-04-04 WO disclosed
EP-3030565-B1 NOVEL SUBSTITUTED CONDENSED PYRIMIDINE COMPOUNDS GRUENENTHAL GMBH (DE) 2017-07-19 EP disclosed
US-9688683-B2 Substituted condensed pyrimidine compounds Grünenthal GmbH (DE) 2017-06-27 US disclosed
US-20160152624-A1 NOVEL SUBSTITUTED CONDENSED PYRIMIDINE COMPOUNDS Grünenthal GmbH (DE) 2016-06-02 US disclosed
US-20040019046-A1 Phenylacetamido-pyrazole derivatives and their use as antitumor agents PHARMACIA ITALIA SPA (IT) 2004-01-29 US disclosed
EP-1345909-A1 PHENYLACETAMIDO-PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS Pharmacia Italia S.p.A. (IT) 2003-09-24 EP disclosed
EP-1155014-B1 NEW BENZIMIDAZOLE COMPOUNDS FOR USE AS ACTIVE THERAPEUTIC SUBSTANCES, PROCESS FOR THE PREPARATION OF THESE COMPOUDNS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PHARMACIA AB (SE) 2003-06-04 EP disclosed
WO-2002048114-A1 PHENYLACETAMIDO- PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS PHARMACIA ITALIA S.P.A. (IT) 2002-06-20 WO disclosed
EP-1155014-A1 NEW BENZIMIDAZOLE COMPOUNDS FOR USE AS ACTIVE THERAPEUTIC SUBSTANCES, PROCESS FOR THE PREPARATION OF THESE COMPOUDNS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM Pharmacia AB (SE) 2001-11-21 EP disclosed
WO-2000043387-A1 NEW BENZIMIDAZOLE COMPOUNDS FOR USE AS ACTIVE THERAPEUTIC SUBSTANCES, PROCESS FOR THE PREPARATION OF THESE COMPOUDNS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PHARMACIA AB (SE) 2000-07-27 WO disclosed
US-5225516-A POLYMERS THE GENERAL ELECTRIC COMPANY, P.L.C. (GB) 1993-07-06 US disclosed
EP-0401532-B1 PROCESS FOR THE PREPARATION OF A STORAGE STABLE LEVULINIC ACID Chemie Linz Gesellschaft m.b.H. (AT) 1993-03-24 EP disclosed
EP-0299205-B1 SUSTAINED RELEASE MICROCAPSULES AND METHOD FOR THE PRODUCTION THEREOF TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM HIGHER EDUCATION (US) 1992-04-15 EP disclosed
EP-0430510-A2 Polymers THE GENERAL ELECTRIC COMPANY, p.l.c. (GB) 1991-06-05 EP disclosed
EP-0401532-A1 Process for the preparation of a storage stable levulinic acid Chemie Linz Gesellschaft m.b.H. (AT) 1990-12-12 EP disclosed
EP-0299205-A1 Sustained release microcapsules and method for the production thereof TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM HIGHER EDUCATION (US) 1989-01-18 EP disclosed
US-4187225-A Novel synthesis of bis pyrazolone oxonol dyes POLAROID CORPORATION (US) 1980-02-05 US disclosed
US-3933798-A Novel bis-pyrazolone oxonol dyes POLAROID CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160152624-A1 NOVEL SUBSTITUTED CONDENSED PYRIMIDINE COMPOUNDS PDE4A, PDE4B, TYMP HSPD1 2415/4885BLM 242/4885HSPE1 2461/4885
US-20040019046-A1 Phenylacetamido-pyrazole derivatives and their use as antitumor agents DCK, CCNK, CDK2 HSPD1 524/4885BLM 2847/4885HSPE1 508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.