Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600767 | 0.88 | MAPT (0.60) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL51509 | 0.83 | RXFP1 (0.79) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL9418310 | 0.83 | RXFP1 (0.79) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL7822074 | 0.82 | MAPT (1.00) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL10600939 | 0.82 | CA2 (0.60) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL11542193 | 0.81 | HPGD (0.71) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL11542196 | 0.80 | MAPT (0.75) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL12495328 | 0.80 | HSD17B2 (0.60) | MAPTRAB9AKMT2ANPC1MEN1 | |
| SCHEMBL23361 | 0.79 | HDAC6 (0.66) | MAPTNPC1HPGDSMN1; SMN2ALDH1A1 | |
| Ethyne SCHEMBL8195983 | 0.79 | RXFP1 (0.73) | MAPTRAB9AKMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040038076-A1 | Poly (paraphenylenevinylene) derivatives and their use as electroluminescence materials | KREUDER WILLI (DE) | 2004-02-26 | — | — | US | disclosed |
| EP-0783555-B1 | POLY(PARAPHENYLENE VINYLENE) DERIVATIVES AND THEIR USE AS ELECTROLUMINESCENT MATERIALS | COVION ORGANIC SEMICONDUCTORS (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-20010031378-A1 | Poly (paraphenylenevinylene) derivatives and their use as electroluminescence materials | KREUDER WILLI (DE) | 2001-10-18 | — | — | US | disclosed |
| EP-0783555-A1 | POLY(PARAPHENYLENE VINYLENE) DERIVATIVES AND THEIR USE AS ELECTROLUMINESCENT MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010617-A1 | POLY(PARAPHENYLENE VINYLENE) DERIVATIVES AND THEIR USE AS ELECTROLUMINESCENT MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-11 | — | — | WO | disclosed |