Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795492 | 1.00 | HTR1A (0.55) | HTR1AADRA1ACCNA2CDK2CCNA1 | |
| SCHEMBL5726470 | 0.81 | CCNA2 (0.53) | CCNA2CDK2CCNA1AKR1C3AKR1C2 | |
| SCHEMBL5727140 | 0.81 | CCNA2 (0.53) | CCNA2CDK2CCNA1AKR1C3AKR1C2 | |
| SCHEMBL5769663 | 0.81 | CCNA2 (0.53) | CCNA2CDK2CCNA1AKR1C3AKR1C2 | |
| SCHEMBL6796688 | 0.78 | HTR1A (0.55) | HTR1AADRA1ACCNA2CDK2CCNA1 | |
| SCHEMBL5204357 | 0.78 | ALDH1A1 (0.57) | HTR1AADRA1ANPC1RAB9AALDH1A1 | |
| SCHEMBL6788874 | 0.78 | HTR1A (0.55) | HTR1AADRA1ACCNA2CDK2CCNA1 | |
| Hydrochloric Acid SCHEMBL8575744 | 0.77 | CPN1 (0.45) | — | |
| SCHEMBL24451811 | 0.76 | CCNA2 (0.46) | CCNA2CDK2CCNA1HRH3HDAC1 | |
| SCHEMBL6625037 | 0.75 | KCNQ2 (0.63) | HTR1AADRA1AKCNQ2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235919-A1 | Phenylacetamido-thiazole derivatives, process for the preparation and their use as antitumor agents | PFIZER ITALIA S.R.I. (IT) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235919-A1 | Phenylacetamido-thiazole derivatives, process for the preparation and their use as antitumor agents | CDK2, CDK1, CDKN1A | HTR1A 3596/4885ADRA1A 1936/4885CCNA2 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.