Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6790705 | 1.00 | GBA1 (0.75) | GBA1ALDH1A1TSHRLMNATDP1 | |
| SCHEMBL18390184 | 0.90 | GBA1 (0.91) | GBA1ALDH1A1TSHRLMNATDP1 | |
| Conduritol B Epoxide SCHEMBL14973473 | 0.86 | GBA1 (1.00) | GBA1ALDH1A1TSHRLMNATDP1 | |
| Conduritol B Epoxide SCHEMBL613363 | 0.86 | GBA1 (1.00) | GBA1ALDH1A1TSHRLMNATDP1 | |
| SCHEMBL6433027 | 0.86 | — | — | |
| Conduritol B Epoxide SCHEMBL16204471 | 0.86 | GBA1 (1.00) | GBA1ALDH1A1TSHRLMNATDP1 | |
| SCHEMBL13580682 | 0.73 | GBA1 (0.44) | GBA1LMNAAPP | |
| SCHEMBL13580053 | 0.73 | GBA1 (0.44) | GBA1LMNAAPP | |
| SCHEMBL13580051 | 0.73 | GBA1 (0.44) | GBA1LMNAAPP | |
| SCHEMBL13580677 | 0.73 | GBA1 (0.44) | GBA1LMNAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152905-A1 | Universal building blocks and support media for synthesis of oligonucleotides and their analogs | ISIS PHARMACEUTICALS, INC. | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152905-A1 | Universal building blocks and support media for synthesis of oligonucleotides and their analogs | POLM, POLRMT, POLB | GBA1 3140/4885ALDH1A1 4408/4885TSHR 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.