Conduritol B Epoxide

Conduritol B Epoxide

SCHEMBL613363

OC1C(O)C(O)C2OC2C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 4/20 1.00
LMNA P02545 2/20 0.46
APP P05067 1/20 0.46
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Conduritol B Epoxide SCHEMBL14973473 1.00 GBA1 (1.00) GBA1LMNAAPPALDH1A1TSHR
Conduritol B Epoxide SCHEMBL29386033 1.00 GBA1 (1.00) GBA1LMNAAPPALDH1A1TSHR
SCHEMBL6433027 1.00
Conduritol B Epoxide SCHEMBL16204471 1.00 GBA1 (1.00) GBA1LMNAAPPALDH1A1TSHR
SCHEMBL18390184 0.95 GBA1 (0.91) GBA1LMNAAPPALDH1A1TSHR
SCHEMBL6790705 0.86 GBA1 (0.75) GBA1LMNAAPPALDH1A1TSHR
SCHEMBL6790708 0.86 GBA1 (0.75) GBA1LMNAAPPALDH1A1TSHR
SCHEMBL12346253 0.80 GBA1 (0.65) GBA1
Cyclophellitol SCHEMBL21778094 0.76 GBA1 (0.58) GBA1LMNAALDH1A1TSHRTDP1
Cyclophellitol SCHEMBL12232222 0.76 GBA1 (0.58) GBA1LMNAALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479735-A Cationic UV curing adhesive and preparation method and application thereof 张河远 2022-05-13 CN claimed
US-20260027213-A1 EPICARDIAL-DERIVED PARACRINE FACTORS FOR REPAIRING CARDIAC TISSUE REGENCOR INC (US) 2026-01-29 US disclosed
US-12458689-B2 Escherichia coli compositions and methods thereof PFIZER INC. (US) 2025-11-04 US disclosed
US-20250205306-A1 USE OF FOLLISTATIN-LIKE 1 (FSTL1) IN CARDIOMETABOLIC HEART FAILURE REGENCOR, INC. 2025-06-26 US disclosed
US-20250114442-A1 ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF PFIZER (US) 2025-04-10 US disclosed
EP-4499125-A1 USE OF FOLLISTATIN-LIKE 1 (FSTL1) IN CARDIOMETABOLIC HEART FAILURE Regencor, Inc. (US) 2025-02-05 EP disclosed
US-12138302-B2 Escherichia coli compositions and methods thereof PFIZER INC. (US) 2024-11-12 US disclosed
US-20240325513-A1 ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF PFIZER (US) 2024-10-03 US disclosed
WO-2023183933-A1 USE OF FOLLISTATIN-LIKE 1 (FSTL1) IN CARDIOMETABOLIC HEART FAILURE REGENCOR, INC. (US) 2023-09-28 WO disclosed
EP-4237428-A2 ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF Pfizer Inc. (US) 2023-09-06 EP disclosed
US-8007814-B2 Therapy for lysosomal enzyme deficiencies UNIVERSITY OF MASSACHUSETTS (US) 2011-08-30 US disclosed
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2011-02-03 US disclosed
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS WARATAH PHARMACEUTICALS INC. (CA) 2011-02-03 US disclosed
EP-1802289-A2 COMPOSITIONS AND THEIR USES FOR LYSOSOMAL ENZYME DEFICIENCIES University of Massachusetts (US) 2007-07-04 EP disclosed
US-20060083718-A1 Novel therapy for lysosomal enzyme deficiencies UNIVERSITY OF MASSACHUSETTS (US) 2006-04-20 US disclosed
WO-2006032039-A2 COMPOSITIONS AND THEIR USES FOR LYSOSOMAL ENZYME DEFICIENCIES UNIVERSITY OF MASSACHUSETTS (US) 2006-03-23 WO disclosed
EP-1172400-B1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY YUPO CORP (JP) 2005-12-28 EP disclosed
US-6586106-B2 Ink transfer, adhesion and aging stability, and being satisfactory in back ghost when offset printing using oxidation polymerization type ink is performed on both faces YUPO CORPORATION (JP) 2003-07-01 US disclosed
US-20020054991-A1 Thermoplastic resin film satisfactory in printability YUPO CORPORATION (JP) 2002-05-09 US disclosed
EP-1172400-A1 THERMOPLASTIC RESIN FILM WITH SATISFACTORY PRINTABILITY Yupo Corporation (JP) 2002-01-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458689-B2 Escherichia coli compositions and methods thereof MRPL21, DDOST, OSTC GBA1 2642/4885LMNA 1242/4885APP 541/4885
US-20110028719-A1 SCREENING METHODS FOR AMYLOID BETA MODULATORS APP, BACE1, IAPP GBA1 163/4885LMNA 1372/4885APP 1/4885
US-20240325513-A1 ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF MRPL21, DDOST, OSTC GBA1 2642/4885LMNA 1242/4885APP 541/4885
US-20260027213-A1 EPICARDIAL-DERIVED PARACRINE FACTORS FOR REPAIRING CARDIAC TISSUE TNNI3, TNNT2, FN1 GBA1 3902/4885LMNA 1602/4885APP 1966/4885
US-20250114442-A1 ESCHERICHIA COLI COMPOSITIONS AND METHODS THEREOF MRPL21, DDOST, STT3A GBA1 2473/4885LMNA 1348/4885APP 1385/4885
US-12138302-B2 Escherichia coli compositions and methods thereof MRPL21, DDOST, STT3A GBA1 2473/4885LMNA 1348/4885APP 1385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.