SCHEMBL6790881

SCHEMBL6790881

CN(CF)c1cccc(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
BCHE P06276 1/20 0.38
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
RIPK1 Q13546 1/20 0.34
AOC3 Q16853 1/20 0.32
KCNH2 Q12809 3/20 0.32
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
MAT2A P31153 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALPL P05186 1/20 0.30
ALPI P09923 1/20 0.30
ALPG P10696 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715884 0.80 ESR1 (0.38) KDM4EALDH1A1SMN1; SMN2TAAR1RIPK1
SCHEMBL7690206 0.78 MAPT (0.46) CES2CES1BCHEKDM4EALDH1A1
SCHEMBL6790356 0.76 SMN1; SMN2 (0.36) CES2CES1BCHEKDM4EALDH1A1
SCHEMBL9287745 0.76 CES2 (0.37) CES2CES1BCHEKDM4EALDH1A1
SCHEMBL30076665 0.76 CES2 (0.37) CES2CES1BCHEKDM4EALDH1A1
SCHEMBL5715946 0.74 MEN1 (0.37) KDM4EALDH1A1SMN1; SMN2KCNH2
SCHEMBL5715959 0.74 MEN1 (0.37) KDM4EALDH1A1SMN1; SMN2KCNH2
SCHEMBL27969319 0.74 CES2 (0.35) CES2CES1BCHEKDM4EALDH1A1
SCHEMBL1241981 0.72 DAO (0.38)
SCHEMBL5716526 0.72 UBE2M (0.32) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed