SCHEMBL679095

SCHEMBL679095

COc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
PTGS1 P23219 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
RAB9A P51151 1/20 0.43
TMPRSS4 Q9NRS4 2/20 0.42
P2RX1 P51575 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
IDO1 P14902 2/20 0.41
EPHX2 P34913 1/20 0.41
KDM1A O60341 1/20 0.41
CES2 O00748 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5782136 0.95 ALDH1A1 (0.58) ALDH1A1RXRARXRBRXRGPTGS1
SCHEMBL12255396 0.91 RXRA (0.43) ALDH1A1RXRARXRBRXRGPTGS1
SCHEMBL17922590 0.89 RXRA (0.42) ALDH1A1RXRARXRBRXRGPTGS1
SCHEMBL257565 0.86 RXRA (0.43) ALDH1A1RXRARXRBRXRGPTGS1
SCHEMBL2522090 0.86 RXRA (0.43) ALDH1A1RXRARXRBRXRGPTGS1
SCHEMBL30181252 0.86 RXRA (0.43) ALDH1A1RXRARXRBRXRGPTGS1
SCHEMBL5783571 0.84 NOTUM (0.51) ALDH1A1RXRARXRBRXRGPTGS1
SCHEMBL5788396 0.84 RXRA (0.45) ALDH1A1RXRARXRBRXRGPTGS1
SCHEMBL1344359 0.84 RXRA (0.42) ALDH1A1RXRARXRBRXRGPTGS1
SCHEMBL14697236 0.84 RXRA (0.42) ALDH1A1RXRARXRBRXRGPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
EP-1917239-A1 FLUOROPROSTAGLANDINS NITRODERIVATIVES Pfizer, Inc. (US) 2008-05-07 EP claimed
WO-2007000642-A1 FLUOROPROSTAGLANDINS NITRODERIVATIVES PFIZER INC. (US) 2007-01-04 WO claimed
WO-2023120250-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, ELECTRONIC DEVICE MANUFACTURING METHOD, AND COMPOUND 富士フイルム株式会社 2023-06-29 WO disclosed
CN-116253606-A Preparation method of aryl difluoromethyl alkyl sulfonyl fluoride compound 上海应用技术大学 2023-06-13 CN disclosed
US-20220145172-A1 POLYMERIC ORGANIC NANOPARTICLES WITH ENHANCED EMISSION Sony Group Corporation (JP) 2022-05-12 US disclosed
US-11230663-B2 Polymeric organic nanoparticles with enhanced emission SONY CORPORATION (JP) 2022-01-25 US disclosed
US-10870715-B2 Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method MITSUI CHEMICALS, INC. (JP) 2020-12-22 US disclosed
EP-3126470-B1 PERYLENE-BASED MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS SONY CORP (JP) 2020-11-04 EP disclosed
US-20200166502-A1 SENSOR FOR THE DETECTION OF BIOMOLECULES SONY CORPORATION (JP) 2020-05-28 US disclosed
EP-3027322-B1 METHOD FOR SORTING CELLS AND/OR PARTICLES SPHERE FLUIDICS LTD (GB) 2020-04-08 EP disclosed
US-6403632-B1 CYCLIC AMIDE DERIVATIVE BRISTOL MYERS SQUIBB PHARMA CO (US) 2002-06-11 US disclosed
US-6376665-B1 ANTIARTHRITIC AGENTS, ANTIINFLAMMATORY AGENTS BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-04-23 US disclosed
EP-1165500-A1 AMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES,TNF-ALPHA,AND AGGRECANASE Du Pont Pharmaceuticals Company (US) 2002-01-02 EP disclosed
WO-2000059874-A1 NOVEL AMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES, TNF-α, AND AGGRECANASE DU PONT PHARMACEUTICALS COMPANY (US) 2000-10-12 WO disclosed
US-6057336-A ANTIINFLAMMATORY AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-02 US disclosed
US-5985920-A COMPOUNDS FOR TREATMENT OF VISION DEFECTS SUCH AS GLAUCOMA ASAHI GLASS COMPANY LTD. (JP) 1999-11-16 US disclosed
EP-0930296-A1 FLUORINATED PROSTAGLANDIN DERIVATIVES AND MEDICINES ASAHI GLASS COMPANY LTD. (JP) 1999-07-21 EP disclosed
US-5886035-A PREVENTIVE AND THERAPEUTICAL MEDICINE FOR EYE DISEASE ASAHI GLASS COMPANY LTD. (JP) 1999-03-23 US disclosed
EP-0850926-A2 Difluoroprostaglandin derivatives and their use ASAHI GLASS COMPANY LTD. (JP) 1998-07-01 EP disclosed