Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6092640 | 0.88 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL6092646 | 0.88 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL6791161 | 0.80 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL5642882 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5644512 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5647713 | 0.77 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL27648316 | 0.76 | PTGS2 (0.97) | PTGS2PTGS1 | |
| SCHEMBL27628664 | 0.76 | PTGS2 (0.97) | PTGS2PTGS1 | |
| SCHEMBL27628401 | 0.76 | PTGS2 (0.97) | PTGS2PTGS1 | |
| SCHEMBL6791167 | 0.75 | PTGS2 (0.50) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806288-B1 | CYCLOOXYGENASE-2 MEDIATED DISORDERS; REDUCES INFLAMMATION; FEWER SIDE EFFECTS | G.D. SEARLE & CO. | 2004-10-19 | — | — | US | disclosed |