Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 6/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680312 | 0.90 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL9570692 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL680228 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL8982806 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL8982802 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL8982810 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL6211963 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL9570701 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL9411006 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL9411090 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108557-A1 | FLUOROQUINOLONE DERIVATIVES FOR OPHTHALMIC APPLICATIONS | ALCON RESEARCH, LTD. (US) | 2012-05-03 | — | — | US | disclosed |
| US-20110160172-A1 | FLUOROQUINOLONE DERIVATIVES FOR OPHTHALMIC APPLICATIONS | ALCON RESEARCH, LTD. (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160172-A1 | FLUOROQUINOLONE DERIVATIVES FOR OPHTHALMIC APPLICATIONS | QARS1, UACA, CYP51A1 | ALDH1A1 4160/4885KDM4E 392/4885HPGD 1869/4885 |
| US-20120108557-A1 | FLUOROQUINOLONE DERIVATIVES FOR OPHTHALMIC APPLICATIONS | QARS1, UACA, CYP51A1 | ALDH1A1 4160/4885KDM4E 392/4885HPGD 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.