SCHEMBL6792073

SCHEMBL6792073

CCCCCCN(CCC(CC)CCCC)c1ccc(F)cc1F

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
SOAT1 P35610 1/20 0.33
CNR2 P34972 1/20 0.33
PPARG P37231 3/20 0.32
PPARA Q07869 3/20 0.32
PPARD Q03181 1/20 0.32
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30
GCGR P47871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715906 1.00 LMNA (0.34) LMNASOAT1CNR2PPARGPPARA
SCHEMBL5716301 0.90 LMNA (0.34) LMNASOAT1CNR2PPARGPPARA
SCHEMBL5715845 0.86 SOAT1 (0.39) SOAT1CNR2PPARGPPARAPPARD
SCHEMBL7649109 0.84 ALDH1A1 (0.37) LMNACNR2PRSS1PRSS2PRSS3
SCHEMBL5715543 0.82 LMNA (0.31) LMNA
SCHEMBL5716188 0.82 LMNA (0.35) LMNA
SCHEMBL5715939 0.81 CNR2 (0.40) SOAT1CNR2PPARGPPARAPPARD
SCHEMBL5716551 0.79 SOAT1 (0.37) SOAT1CNR2PPARGPPARAPPARD
SCHEMBL6791324 0.79 LMNA (0.32) LMNASOAT1CNR2
SCHEMBL6790671 0.78 LMNA (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed