Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.53 |
| ▸ | PLD2 | O14939 | 10/20 | 0.52 |
| ▸ | PLD1 | Q13393 | 10/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807222 | 0.94 | PLD2 (0.56) | OPRL1PLD2PLD1CCR1CHRM1 | |
| SCHEMBL4807214 | 0.94 | PLD2 (0.56) | OPRL1PLD2PLD1CCR1CHRM1 | |
| SCHEMBL11648606 | 0.88 | OPRL1 (0.63) | OPRL1PLD2PLD1CCR1CHRM1 | |
| SCHEMBL6697552 | 0.87 | PLD2 (0.57) | OPRL1PLD2PLD1CCR1CHRM1 | |
| SCHEMBL4805878 | 0.87 | PLD2 (0.57) | OPRL1PLD2PLD1CCR1CHRM1 | |
| SCHEMBL4805869 | 0.87 | PLD2 (0.57) | OPRL1PLD2PLD1CCR1CHRM1 | |
| SCHEMBL4808944 | 0.85 | OPRL1 (0.57) | OPRL1PLD2PLD1CCR1CHRM1 | |
| SCHEMBL4809038 | 0.85 | CCR1 (0.55) | OPRL1PLD2PLD1CCR1OPRM1 | |
| SCHEMBL4809028 | 0.85 | CCR1 (0.55) | OPRL1PLD2PLD1CCR1OPRM1 | |
| Hydrochloric Acid SCHEMBL4805706 | 0.84 | OPRL1 (0.56) | OPRL1PLD2PLD1CCR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116435-A1 | Benzimidazol derivatives modulate chemokine receptors | ASTRAZENECA AB (SE) | 2004-06-17 | — | — | US | disclosed |