Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6789577 | 0.99 | PARP1 (0.44) | PARP1HPGDROCK2ROCK1MAPT | |
| SCHEMBL6787980 | 0.92 | ROCK2 (0.50) | PARP1HPGDROCK2ROCK1MAPT | |
| SCHEMBL6786124 | 0.92 | ROCK2 (0.48) | PARP1HPGDROCK2ROCK1MAPT | |
| SCHEMBL6788665 | 0.91 | ROCK2 (0.49) | PARP1HPGDROCK2ROCK1MAPT | |
| SCHEMBL6783527 | 0.91 | ROCK2 (0.49) | PARP1HPGDROCK2ROCK1MAPT | |
| SCHEMBL6782611 | 0.91 | ROCK2 (0.46) | PARP1HPGDROCK2ROCK1MAPT | |
| Hydrochloric Acid SCHEMBL6787368 | 0.91 | ROCK2 (0.47) | PARP1HPGDROCK2ROCK1MAPT | |
| Hydrochloric Acid SCHEMBL6788510 | 0.90 | ROCK2 (0.49) | PARP1HPGDROCK2ROCK1MAPT | |
| Hydrochloric Acid SCHEMBL6786676 | 0.90 | ROCK2 (0.45) | PARP1HPGDROCK2ROCK1MAPT | |
| Hydrochloric Acid SCHEMBL6787219 | 0.90 | ROCK2 (0.49) | PARP1HPGDROCK2ROCK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677333-B1 | ANTIISCHEMIC AGENTS; BRAIN, CARDIOVASCULAR, MUSCULAR, AND GASTROINTESTINAL DISORDERS; ANALGESICS, ANTIDIABETIC AGENTS; RETROVIRUS SENSITIZERS; ALZHEIMER*S DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-01-13 | — | — | US | claimed |
| EP-1148053-A1 | 2H-PHTHALAZIN-1-ONE DERIVATIVES AND DRUGS COMPRISING THESE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-24 | — | — | EP | claimed |