SCHEMBL6792812

SCHEMBL6792812

CN(CCc1ccccn1)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cn1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMO Q99835 2/20 0.55
DGAT1 O75907 5/20 0.48
NR3C1 P04150 2/20 0.47
TRPV1 Q8NER1 1/20 0.46
MTTP P55157 6/20 0.46
APOB P04114 3/20 0.46
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6799363 0.89 SMO (0.56) SMONR3C1TRPV1MTTPAPOB
SCHEMBL6794354 0.87 SMO (0.61) SMONR3C1TRPV1MTTPAPOB
SCHEMBL6795015 0.86 SMO (0.57) SMONR3C1TRPV1MTTPAPOB
SCHEMBL6799155 0.85 SMO (0.57) SMOTRPV1MTTPAPOB
SCHEMBL6790830 0.85 SMO (0.56) SMOTRPV1MTTPAPOB
SCHEMBL6792796 0.84 SMO (0.59) SMONR3C1TRPV1MTTPAPOB
SCHEMBL6795032 0.83 SMO (0.54) SMONR3C1TRPV1MTTPAPOB
SCHEMBL6788361 0.82 SMO (0.56) SMONR3C1TRPV1MTTPAPOB
SCHEMBL6794869 0.82 SMO (0.56) SMONR3C1TRPV1MTTPAPOB
SCHEMBL6795426 0.82 SMO (0.56) SMONR3C1TRPV1MTTPAPOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed
EP-1326835-A1 BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-07-16 EP disclosed
WO-2002028835-A1 BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-04-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 SMO 2094/4885DGAT1 386/4885NR3C1 1665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.