SCHEMBL6792929

SCHEMBL6792929

CC(C)(CO)c1ccc(Nc2nc(Nc3ccc4c(c3)OCCO4)ncc2F)cc1.CCOC(=O)C(C)(C)c1ccc(NC2=NC(Cl)(Nc3ccc4c(c3)OCCO4)NC=C2F)cc1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SYK P43405 14/20 0.46
EGFR P00533 6/20 0.41
BTK Q06187 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL655795 0.87 MAPT (0.39)
SCHEMBL655873 0.83 SYK (0.61) SYKEGFR
SCHEMBL655302 0.78 SYK (0.68) SYKEGFR
SCHEMBL655289 0.69 SYK (0.69) SYKEGFR
SCHEMBL656378 0.69 SYK (0.67) SYK
SCHEMBL655791 0.69 SYK (0.67) SYK
SCHEMBL655299 0.68 SYK (0.67) SYKEGFR
SCHEMBL655167 0.68 SYK (0.78) SYKEGFR
SCHEMBL655775 0.68 SYK (0.78) SYKEGFR
SCHEMBL6016741 0.68 SYK (0.62) SYKEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040029902-A1 Antiinflamamtory agents MIDCAP FINANCIAL TRUST 2004-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029902-A1 Antiinflamamtory agents FCER2, FCGR1A, HNMT SYK 251/4885EGFR 1288/4885BTK 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.