Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.63 |
| ▸ | SYK | P43405 | 16/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.61 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.61 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757118 | 0.86 | AURKA (0.63) | AURKASYKMAPK8AURKBCDK19 | |
| SCHEMBL659274 | 0.85 | SYK (0.67) | AURKASYKMAPK8AURKBCDK19 | |
| SCHEMBL27631577 | 0.82 | SYK (0.61) | AURKASYKMAPK8AURKBCDK19 | |
| SCHEMBL655134 | 0.81 | SYK (0.77) | AURKASYK | |
| SCHEMBL657059 | 0.81 | SYK (0.77) | AURKASYK | |
| SCHEMBL27631462 | 0.80 | AURKA (0.70) | AURKASYKMAPK8AURKBCDK19 | |
| SCHEMBL655720 | 0.79 | SYK (0.76) | AURKASYK | |
| SCHEMBL656282 | 0.79 | SYK (0.76) | AURKASYK | |
| R-112 SCHEMBL655935 | 0.79 | SYK (1.00) | AURKASYKMAPK8AURKBCDK19 | |
| R-112 SCHEMBL29360016 | 0.79 | SYK (1.00) | AURKASYKMAPK8AURKBCDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029902-A1 | Antiinflamamtory agents | MIDCAP FINANCIAL TRUST | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029902-A1 | Antiinflamamtory agents | FCER2, FCGR1A, HNMT | AURKA 1221/4885SYK 251/4885MAPK8 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.