Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 8/20 | 0.51 |
| ▸ | TSPO | P30536 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565495 | 0.95 | TSPO (0.50) | STSTSPOCA2CA9CA1 | |
| SCHEMBL6799059 | 0.93 | TSPO (0.46) | STSTSPOCA2CA9CA1 | |
| SCHEMBL6800139 | 0.81 | STS (0.55) | STSCA2CA9CA1CA12 | |
| SCHEMBL2240045 | 0.80 | STS (0.58) | STSCA2CA9CA1CA12 | |
| SCHEMBL6795598 | 0.76 | MEN1 (0.60) | STSCA2CA9CA1CA12 | |
| SCHEMBL4667289 | 0.76 | STS (0.54) | STSCA2CA9CA1CA12 | |
| SCHEMBL6799122 | 0.76 | STS (0.54) | STSCA2CA9CA1CA12 | |
| SCHEMBL6802253 | 0.75 | STS (0.58) | STSCA2CA9CA1CA12 | |
| SCHEMBL14596833 | 0.74 | STS (0.61) | STSCA2CA9CA1CA12 | |
| SCHEMBL6801979 | 0.74 | LTB4R2 (0.53) | TSPOLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |