Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.53 |
| ▸ | TSPO | P30536 | 5/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799498 | 0.87 | TSPO (0.51) | LTB4R2TSPOPDK2PDK4CYP3A4 | |
| SCHEMBL10926482 | 0.80 | ALDH1A1 (0.48) | CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL27872334 | 0.78 | ESR1 (0.40) | PDK2PDK4CYP3A4CYP2C9PDK1 | |
| SCHEMBL9645342 | 0.78 | ESR1 (0.40) | PDK2PDK4CYP3A4CYP2C9PDK1 | |
| SCHEMBL5694553 | 0.78 | TSPO (0.72) | LTB4R2TSPOALDH1A1 | |
| SCHEMBL9416644 | 0.78 | ALDH1A1 (0.50) | CYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL1259310 | 0.77 | PDK1 (0.58) | LTB4R2PDK2PDK4PDK1ESR1 | |
| SCHEMBL935744 | 0.77 | MLYCD (0.41) | ESR1ESR2ALDH1A1 | |
| SCHEMBL29588899 | 0.77 | ESR1 (0.42) | LTB4R2PDK2PDK4CYP3A4CYP2C9 | |
| SCHEMBL20219028 | 0.77 | TSPO (0.69) | LTB4R2TSPOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |