Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 18/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 13/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6796562 | 0.88 | OPRD1 (0.98) | OPRD1OPRM1OPRK1 | |
| SCHEMBL3131262 | 0.85 | OPRD1 (0.79) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6796353 | 0.84 | OPRD1 (0.79) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8529558 | 0.84 | OPRD1 (1.00) | OPRD1OPRM1OPRK1 | |
| SCHEMBL13620476 | 0.84 | OPRD1 (0.78) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6795823 | 0.84 | OPRD1 (1.00) | OPRD1OPRM1OPRK1 | |
| SCHEMBL13620474 | 0.84 | OPRD1 (0.78) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6791944 | 0.83 | OPRD1 (1.00) | OPRD1OPRM1OPRK1 | |
| SCHEMBL4935999 | 0.83 | OPRD1 (0.80) | OPRD1OPRM1OPRK1 | |
| SCHEMBL5172313 | 0.83 | OPRD1 (0.78) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6680321-B1 | 4-((1-PIPERAZINYLMETHYL)-BENZAMIDE DERIVATIVES; HYPOTENSIVE AGENTS; IMMUNOMODULATORS | ASTRAZENECA CANADA, INC. (CA) | 2004-01-20 | — | — | US | claimed |