⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099497 | 0.82 | NOS1 (0.44) | — | |
| SCHEMBL22613260 | 0.76 | — | — | |
| SCHEMBL9046922 | 0.72 | NOS1 (0.36) | — | |
| SCHEMBL9426491 | 0.71 | ADORA3 (0.44) | — | |
| SCHEMBL9047243 | 0.70 | NOS1 (0.34) | — | |
| SCHEMBL9098247 | 0.70 | ADORA3 (0.36) | — | |
| SCHEMBL9098178 | 0.69 | NOS1 (0.41) | — | |
| SCHEMBL9098659 | 0.69 | EPHX2 (0.35) | — | |
| SCHEMBL22020712 | 0.68 | — | — | |
| SCHEMBL8940793 | 0.67 | NOS1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743811-B2 | MICROBIOCIDES | PHARMACIA & UPJOHN COMPANY | 2004-06-01 | — | — | US | disclosed |
| US-20020169191-A1 | Oxazolidinone compounds and methods of preparation and use thereof | PHARMACIA & UPJOHN COMPANY (US) | 2002-11-14 | — | — | US | disclosed |
| US-6441005-B1 | BACTERICIDES, ANTIBIOTICS AND MICROBIOCIDES | PHARMACIA & UPJOHN COMPANY | 2002-08-27 | — | — | US | disclosed |
| EP-1200416-A1 | OXAZOLIDINONES AND THEIR USE AS ANTIINFECTIVES | Pharmacia & Upjohn Company (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009107-A1 | OXAZOLIDINONES AND THEIR USE AS ANTIINFECTIVES | PHARMACIA & UPJOHN COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |