Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804922 | 0.84 | NOS1 (0.33) | NOS1NOS3NOS2MEN1GAA | |
| SCHEMBL27667862 | 0.80 | GABRR1 (0.45) | GABRR1MEN1GAAKMT2ACPB2 | |
| SCHEMBL19621729 | 0.80 | GABRR1 (0.35) | GABRR1 | |
| SCHEMBL856794 | 0.76 | NOS1 (0.40) | NOS1NOS3NOS2GABRR1MEN1 | |
| SCHEMBL6068166 | 0.76 | GABRR1 (0.50) | NOS1NOS3NOS2GABRR1MEN1 | |
| SCHEMBL30471715 | 0.76 | NOS1 (0.40) | NOS1NOS3NOS2GABRR1MEN1 | |
| SCHEMBL7110422 | 0.76 | NOS1 (0.36) | NOS1NOS3NOS2GABRR1MEN1 | |
| SCHEMBL6797401 | 0.76 | NOS1 (0.36) | NOS1NOS3NOS2GABRR1MEN1 | |
| SCHEMBL30860145 | 0.76 | NOS1 (0.40) | NOS1NOS3NOS2GABRR1MEN1 | |
| SCHEMBL19542924 | 0.74 | MAPK1 (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6750219-B1 | HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISTIC ACTIVITY, GP IIB/IIIA ANTAGONISTIC ACTIVITY, AND/OR HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY AND ALSO HAVING EXCELLENT WATER SOLUBILITY | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-06-15 | — | — | US | disclosed |
| EP-1209152-A1 | OMEGA-AMINO-ALPHA-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-05-29 | — | — | EP | disclosed |