Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794664 | 0.84 | NOS1 (0.35) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL13484721 | 0.78 | SRR (0.34) | KMT2AMEN1GAA | |
| SCHEMBL7328879 | 0.78 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL19542924 | 0.78 | MAPK1 (0.40) | KMT2ALMNACYP2D6CA1CA2 | |
| SCHEMBL20569401 | 0.77 | TDP1 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL3205535 | 0.77 | NOS1 (0.34) | NOS1NOS3NOS2KMT2ALMNA | |
| SCHEMBL6932447 | 0.76 | KMT2A (0.36) | NOS1NOS3NOS2KMT2ALMNA | |
| SCHEMBL27747509 | 0.76 | NOS1 (0.36) | NOS1NOS3NOS2KMT2ALMNA | |
| SCHEMBL17662428 | 0.75 | LMNA (0.32) | NOS1NOS3NOS2KMT2ALMNA | |
| SCHEMBL5665277 | 0.74 | TSHR (0.38) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6750219-B1 | HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISTIC ACTIVITY, GP IIB/IIIA ANTAGONISTIC ACTIVITY, AND/OR HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY AND ALSO HAVING EXCELLENT WATER SOLUBILITY | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-06-15 | — | — | US | disclosed |
| EP-1209152-A1 | OMEGA-AMINO-ALPHA-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-05-29 | — | — | EP | disclosed |