Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.59 |
| ▸ | MAPT | P10636 | 10/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125016 | 0.85 | MEN1 (0.68) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL6799176 | 0.78 | MAPT (0.68) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL20020500 | 0.75 | MEN1 (0.69) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL125195 | 0.75 | MAPT (1.00) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL8441345 | 0.75 | MEN1 (1.00) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL28744558 | 0.75 | MEN1 (0.69) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL8140377 | 0.74 | MEN1 (0.63) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL11167414 | 0.73 | MAPT (0.56) | MEN1KMT2AMAPTRAB9AHSD17B10 | |
| SCHEMBL24156370 | 0.72 | CRBN (0.73) | MEN1KMT2AMAPTRAB9AMAOA | |
| SCHEMBL10501019 | 0.72 | MAOA (0.41) | MEN1KMT2AMAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716845-B2 | Barbituric acid derivatives | HOFFMANN-LA ROCHE INC. | 2004-04-06 | — | — | US | disclosed |