Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.68 |
| ▸ | MEN1 | O00255 | 9/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125016 | 0.85 | MEN1 (0.68) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL7701199 | 0.81 | MEN1 (1.00) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL6794971 | 0.78 | MEN1 (0.59) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL5293066 | 0.78 | MGLL (0.57) | MAPTMEN1KMT2AMGLLUSP2 | |
| SCHEMBL17281692 | 0.76 | MGLL (0.65) | MAPTKMT2ASMN1; SMN2MGLLUSP2 | |
| SCHEMBL8441345 | 0.75 | MEN1 (1.00) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL28744558 | 0.75 | MEN1 (0.69) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL20020500 | 0.75 | MEN1 (0.69) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL125195 | 0.75 | MAPT (1.00) | MAPTMEN1KMT2ARAB9AHSD17B10 | |
| SCHEMBL8140377 | 0.74 | MEN1 (0.63) | MAPTMEN1KMT2ARAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716845-B2 | Barbituric acid derivatives | HOFFMANN-LA ROCHE INC. | 2004-04-06 | — | — | US | disclosed |