⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960655 | 0.95 | — | — | |
| SCHEMBL11253033 | 0.93 | LMNA (0.39) | — | |
| SCHEMBL8960929 | 0.83 | — | — | |
| SCHEMBL670979 | 0.81 | LMNA (0.46) | — | |
| SCHEMBL4905354 | 0.81 | LMNA (0.46) | — | |
| SCHEMBL5985551 | 0.80 | — | — | |
| SCHEMBL14247972 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL11389165 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL14317720 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL3253778 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |
| US-6407284-B1 | CONTACTING WITH ENZYME; HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |
| CN-1066135-C | Ysnthetic excitatory amino acids | LILLY CO ELI (US) | 2001-05-23 | — | — | CN | disclosed |
| EP-1046712-A2 | Method of resolving 2-oxobicyclo (3.1.0) hexane-6-carboxylic acid derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-25 | — | — | EP | disclosed |
| US-5925680-A | Synthetic excitatory amino acids | ELI LILLY AND COMPANY (US) | 1999-07-20 | — | — | US | disclosed |
| US-5925782-A | Synthetic excitatory amino acids | ELI LILLY AND COMPANY (US) | 1999-07-20 | — | — | US | disclosed |
| EP-0696577-B1 | Synthetic excitatory amino acids | LILLY CO ELI (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5750566-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| CN-1123272-A | Ysnthetic excitatory amino acids | LILLY CO ELI (US) | 1996-05-29 | — | — | CN | disclosed |
| WO-1996005175-A1 | SYNTHETIC EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 1996-02-22 | — | — | WO | disclosed |
| EP-0696577-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0693284-A1 | PROSTACYCLIN-CONTAINING OLEAGINOUS OINTMENT | TEIJIN LIMITED (JP) | 1996-01-24 | — | — | EP | disclosed |