Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.64 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.64 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.59 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.58 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795520 | 1.00 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6796548 | 0.94 | MEN1 (0.67) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6796550 | 0.94 | MEN1 (0.67) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL15421524 | 0.94 | MEN1 (0.67) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1241572 | 0.94 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29518211 | 0.87 | CSNK2A2 (0.78) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL22505155 | 0.87 | CSNK2A2 (0.78) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6799713 | 0.85 | POLB (0.71) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6799710 | 0.85 | POLB (0.71) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2131623 | 0.85 | DAPK3 (0.75) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | WARNER-LAMBERT COMPANY LLC | 2004-09-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | APP, PSEN1, PSEN2 | ALDH1A1 905/4885KDM4E 4805/4885MAPT 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.