Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27805818 | 0.81 | KMT2A (0.77) | KMT2AALDH1A1HTTSMN1; SMN2GLA | |
| SCHEMBL3535267 | 0.81 | KMT2A (0.56) | KMT2AALDH1A1HTTSMN1; SMN2GLA | |
| SCHEMBL28382224 | 0.79 | ALDH1A1 (0.75) | KMT2AALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL7193170 | 0.78 | KMT2A (0.63) | KMT2AHTTSMN1; SMN2GLARAB9A | |
| SCHEMBL2450877 | 0.75 | KMT2A (0.69) | KMT2AALDH1A1HTTSMN1; SMN2GLA | |
| SCHEMBL3536797 | 0.75 | KMT2A (0.51) | KMT2AHTTSMN1; SMN2GLARAB9A | |
| SCHEMBL653632 | 0.74 | KMT2A (0.67) | KMT2AALDH1A1HTTSMN1; SMN2GLA | |
| SCHEMBL395690 | 0.74 | KMT2A (0.67) | KMT2AALDH1A1HTTSMN1; SMN2GLA | |
| SCHEMBL28358852 | 0.74 | KMT2A (0.67) | KMT2AALDH1A1HTTSMN1; SMN2GLA | |
| SCHEMBL3462830 | 0.74 | KMT2A (0.67) | KMT2AALDH1A1HTTSMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026846-A1 | DNA-TARGETED BENZOTRIAZINE 1,4-DIOXIDES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2004-04-01 | — | — | WO | disclosed |